Hans Kainz, University of Vienna, Austria

Massimo Sartori, University of Twente, Netherlands

Helping experts

Christopher Carty, Griffith University, Australia

Brian Horsak, University Applied Science St. Pölten, Austria

Bernhard Guggenberger, Medical University Graz, Austria

Andreas Habersack, Medical University Graz, Austria

Date and place

21 September 13:30 - 17:30

Croke Park, Hogan Mezzanine Foyer, Level 4, Jones Road, Drumcondra, Dublin 3

For arrival details, map and the ESMAC 2022 venue floorplan please see

General information

In this seminar, we will show how you can use musculoskeletal models in isolation as well as in combination with real gait analysis data to address clinically relevant research questions. Amongst others, we will show a fast and easy workflow to estimate muscle-tendon kinematics (e.g., length and moment arms), perform virtual surgeries to simple musculoskeletal systems and evaluate the impact on musculoskeletal function. Moreover, we will show how to estimate muscle force via forward and inverse dynamics formulations, e.g., use electromyography-informed simulations to account for muscle co-contractions. Participants of the seminar should bring their own laptop with pre-installed software (i.e., OpenSim 4.4, Notepad++, Mokka) for carrying out the hands-on exercises. By the end of this seminar, you will understand basic principles of musculoskeletal modelling and you will be able to carry out basic analyses of musculoskeletal function.  

Preparation for the seminar

Please download and install OpenSim 4.4, notepad++ and mokka on your laptop.

OpenSim 4.4



Please bring your laptop and a mouse for carrying out the hands-on exercises at the seminar.

We encourage all participant to complete the ‘Tutorial 1 – Intro to Musculoskeletal Modeling’ prior to the seminar.


1. Seminar overview

2. Introduction to the OpenSim framework (+hands-on)

3. Difference conventional clinical gait model versus musculoskeletal models

4. Estimating muscle-tendon length (+hands-on)

5. Data import, scaling and inverse kinematics (+hands-on)

Break 30 minutes

6. Clinical applications of musculoskeletal modelling

7. Simulating a surgery (+hands-on)

8. Typical simulation pipeline (from external to internal biomechanics)

9. Impact of geometry on simulation output (hands-on)

10. Future outlook: EMG-informed modelling

11. Final discussion